Patient_Appeal_Evie_Hodgson_hospital_2

What is a blood disorder?

You might need a stem cell transplant if you have a blood disorder, just like Evie (left) did. On this webpage, we'll explain what a blood disorder is and give more information on specific types.

What are blood disorders?

Video transcription

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Anthony Nolan saves the lives of people with blood cancers and disorders.
We match people willing to donate their stem cells, to people with blood
cancer and disorders, in need of a life saving transplant.
But what are blood disorders? And how do they happen?
Your blood is very important for keeping you fit and healthy.
It's made up of different types of cells, including
red blood cells, for carrying oxygen,
platelets to help blood clots, and white blood cells,
that fight infections.
These all start as stem cells,
which can turn into any type of blood cell, as they divide and mature.
When someone has a blood disorder, it's likely that there's a problem with this stage in the process.
And some of the cells in the blood can't do their jobs properly.
With blood disorders,
many of these of this problems occur, because of a faulty gene that was inherited at birth.
However, others can occur without an obvious reason.
There are lots of different blood disorders,
and they are treated in different ways, depending on their types and severity.
Only some people with blood disorders will need a stem cell transplant,
usually only if other treatments have been unsuccessful.
If you'd like more information, or support,
the Anthony Nolan's patient services team, is here for you.

Your blood is made up of different cell types, including:

  • red blood cells for carrying oxygen
  • white blood cells that fight infections
  • platelets to help blood clot.

They all originally come from stem cells, which have the potential to develop into any type of blood cell as they divide and mature.

If you have a blood disorder, it’s likely that there is a problem with a stage in this process. This means that some of the cells in your blood cannot properly perform the job they are designed to do.

Many of these problems occur because of a faulty gene that was inherited at birth. However, others, such as myelodysplastic syndromes and autoimmune diseases, are not inherited and can occur without an obvious reason.

There are lots of different blood disorders and they are treated in different ways depending on their type and severity. A few of them can develop into blood cancers over time. Only some people with blood disorders will need a stem cell transplant – usually only if other treatments have been unsuccessful.

Different types of blood disorder

Some of the more common blood disorders that might need a stem cell transplant are listed below. Each section provides additional information and links to organisations that offer advice and support.

The What are my treatment options? section looks at other possible ways that your medical team may decide to treat your blood disorder – either before or instead of a stem cell transplant.

Information last updated: 25/02/2025

Next review due: 25/02/2026